The Science Behind CBD and THC: How They Affect Your Body
Posted by The Purple Shop on 2025 Jul 16th
CBD and THC are two of the most well-known cannabinoids, but they both affect the body in different ways. While THC is known for producing a high, CBD offers a more relaxing effect on the body.
In this blog, we will explore how each interacts with your body and how combining them might even offer better results.

How Does CBD Affect Your Body?
CBD interacts with the endocannabinoid system of the body, directly influencing mood, pain, and sleep. CBD can cause side effects like dry mouth and drowsiness, but it also has a number of other effects on the body.
- It Doesn't Cause a High: Unlike THC, CBD is non-psychoactive, meaning it won’t make you feel intoxicated or give you a high.
- May Reduce Stress and Anxiety: Many users report a calming effect, which makes CBD a popular option for managing daily stress or anxiety.
- Can Help with Inflammation: CBD is widely used for its potential anti-inflammatory properties, offering relief from soreness and chronic discomfort.
- Improves Rest and Relaxation: Some people use CBD to improve their sleep or to unwind at the end of a long day.
What Does THC Do to Your Body?
THC, the primary psychoactive component in cannabis, affects the body by interacting with the cannabinoid receptors in the brain. Both THC and CBD interact with the body's endocannabinoid system, but THC binds directly to CB1 receptors, while CBD interacts with them indirectly.
- Creates a high: THC binds directly to CB1 receptors in the brain, producing the euphoric or intoxicating effects commonly associated with cannabis.
- Alters Mood and Perception: It can enhance sensory perception, affect your perception of time, and create feelings of happiness or even anxiety in some users.
- Stimulates Appetite: THC can increase hunger and make food seem more appealing to the user.
- May Help Reduce Pain: THC has pain-relieving properties, making it useful for people managing chronic pain or discomfort.
- Can Aid Sleep: In some cases, THC helps people fall asleep more easily, especially in higher doses.
- Impacts Memory and Focus: THC can temporarily impair short-term memory, concentration, and coordination, which is why caution is needed during use.
What Happens When You Take CBD and THC Together?
When used together, CBD and THC can produce an entourage effect, where the combination enhances the overall therapeutic benefits. This combined effect may provide better relief from symptoms such as pain, inflammation, anxiety, and nausea compared to using either of the drugs alone.
Not only is it safe to take CBD and THC together, but the pairing may also improve the experience. CBD can help reduce the intensity of THC’s psychoactive effects, making the overall high feel more balanced.
Tips for Trying CBD and THC Safely
- Start with a low dose, especially if you are new to cannabis products. Slowly increase the dosage until you find the right balance that is safe for you.
- Pay attention to the CBD-to-THC ratio in each product.
- Always read the product label and check for third-party lab testing to ensure purity and accurate dosing.
- There are a number of methods to take both these drugs: through oils, edibles, or vaping. Choose a method that suits you the best.
- Avoid combining cannabis with alcohol or medications without medical advice, as harmful or unexpected interactions may occur.
- Try THC in a calm and familiar environment to ensure that the experience is safe and comfortable for you.
- Everyone reacts differently to the drugs. So, be mindful of how your body responds and adjust your usage accordingly.
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